C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/234, 260/310
C07D 277/34 (2006.01) A61K 31/425 (2006.01) C07D 417/12 (2006.01)
Patent
CA 1237436
A B S T R A C T The Application concerns 4-oxothiazolidin-2- ylidene-acetamide derivatives of the general formula I Image (I), in which R1 signifies a hydrogen atom, a saturated or unsaturated, straight-chained or branched aliphatic hydrocarbon radical with up to 4 carbon atoms, an aryl or aralkyl group, R2 signifies a hydrogen atom or a straight-chained or branched alkyl- or alkylamino- alkyl radical with up to 9 carbon atoms, X signifies a valence bond or a straight-chained or branched alkylene chain with up to 4 carbon atoms and the radicals R3, R4, and R5, which can be the same or different, signify a hydrogen atom, a straight-chained or branched alkyl radical with up to 4 carbon atoms, a straight-chained or branched alkoxy or alkylthio group with up to 4 carbon atoms, whereby two neigh- bouring radical can together also form a methylenedioxy or ethylenedioxy group, a halogen atom, a hydroxy group, a nitro group, a carboxyl group or a lower alkoxycarbonyl radical with up to 5 carbon atoms and R6 and R7 which can be the same or different signify a hydrogen atom or a straight-chained or branched alkyl radical containing up to 4 carbon atoms. The compounds I are prepared by means of analogous processes and used in the combating of diseases of the CNS, especially of epilepsy.
453789
Bartoszyk Gerd
Fritschi Edgar
Hartenstein Johannes
Herrmann Manfred
Satzinger Gerhard
Godecke Aktiengesellschaft
Smart & Biggar
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