4-phenoxypiperidines, process for their preparation, their...

C - Chemistry – Metallurgy – 07 – D

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260/292.2, 260/2

C07D 211/44 (2006.01) C07D 211/48 (2006.01) C07D 211/52 (2006.01) C07D 211/94 (2006.01)

Patent

CA 1147733

Abstract The invention relates to new co pounds of the formula Image (I) wherein R1 denotes a hydrogen atom, an alkyl group with 1 to 5 carbon atoms, an alkenyl group with 3 to 5 carbon atoms, a cycloalkylmethyl group with 3 to 7 carbon atoms in the cycloalkyl part or a phenylalkyl group with 1 to 3 car- bon atom in the alkyl part, R2 denotes a hydrogen atom, a nitro group, an amino group or an acyl- amino group and R3 denotes a phenyl group or a benzyl group, and their N-oxides and their acid addition salt. The compounds display an antiptotic action coupled with an analgesic action and may thus be use as medicaments. They also re- present useful intermediates to known pharmacologically active 4-phenoxy- piporidines.

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