4-phenyl-3-substituted 1,4-dihydropyridine esters

Details 4-phenyl-3-substituted 1,4-dihydropyridine esters 4-phenyl-3-substituted 1,4-dihydropyridine esters

C - Chemistry, Metallurgy

07

D

C07D 211/90 (2006.01) A61K 31/44 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2137519

4-Phenyl-3-substituted 1,4-dihydropyridine esters are prepared by reaction of benzaldehydes with ketoesters and enamines, if appropriate with isolation of the ylidene intermediate products, or by esterification of corres- ponding dihydropyridinecarboxylic acids with alcohols. The new 4-phenyl-3-substituted 1,4-dihydropyridine esters can be employed as active compounds in medicaments for the treatment of the central nervous system, in parti- cular as cerebral therapeutics.

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