4-phenyl-5-0x0-l,4,5,6,7,8-hexahydr0quin0line derivatives as...

Details 4-phenyl-5-0x0-l,4,5,6,7,8-hexahydr0quin0line derivatives as... 4-phenyl-5-0x0-l,4,5,6,7,8-hexahydr0quin0line derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 215/48 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61P 5/24 (2006.01) A61P 15/00 (2006.01) C07D 215/20 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2607106

The present invention- relates to 2-methyl-4-phenyl-5-oxo-1 ,4,5,6,7,8- hexahydroquinoline derivatives having the general Formula (I) wherein the substituents are defined as in the description, or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives, as well as to the use of these 2- methyl-4-phenyl-5-oxo-1 ,4,5,6,7,8-hexahydroquinoline derivatives in therapy, more specifically for the treatment of fertility disorders.

L'invention concerne un dérivé de 2-méthyl-4-phényl-5-oxo-1,4,5,6,7,8-hexahydroquinoline de formule (I). Dans cette formule, les substituants sont définis dans la description. L'invention concerne également un sel pharmaceutiquement acceptable de ces dérivés. L'invention concerne encore des compositions pharmaceutiques comprenant ces dérivés et l'utilisation de ses dérivés en thérapie, en particulier pour traiter des troubles de stérilité.

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