C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/34 (2006.01) A61K 31/451 (2006.01) A61P 25/00 (2006.01) C07D 401/06 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2522214
The subject invention relates to 4-phenyl-piperidine derivatives of formula (I), pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by an opioid receptor. The subject also particularly relates to using such derivatives to treat certain disease states, disorders and conditions, for example irritable bowel syndrome, drug addiction or dependency, including alcohol addiction, depression, anxiety, schizophrenia, anxiety, schizophrenia and eating disorders, among numerous other disease states, disorders and conditions as more fully described herein.
L'invention concerne des dérivés de 4-phényle-pipéridine de formule I, des compositions pharmaceutiques qui contiennent ces dérivés et des méthodes d'utilisation de ces dérivés pour traiter des états pathologiques, troubles et conditions qui impliquent un récepteur opioïde. L'invention concerne notamment l'utilisation de ces dérivés pour traiter certains états pathologiques, troubles et conditions tels que le côlon irritable, la pharmacodépendance ou la toxicomanie, y compris l'alcoolisme, la dépression, l'anxiété, la schizophrénie et les troubles de la nutrition, parmi de nombreux autres états pathologiques, troubles et conditions qui sont décrits plus en détail dans la demande de brevet.
Coe Jotham Wadsworth
Guediche Sara Ann
Liras Spiros
Mchardy Stanton Furst
Pfizer Products Inc.
Smart & Biggar
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