4-phenyl piperidine sulfonyl glycine transporter inhibitors

Details 4-phenyl piperidine sulfonyl glycine transporter inhibitors 4-phenyl piperidine sulfonyl glycine transporter inhibitors

A - Human Necessities

61

K

A61K 31/445 (2006.01) C07D 211/54 (2006.01)

Patent

CA 2544981

The present invention is directed to compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergic or glutamatergic neurotransmission dysfunction and diseases in which the glycine transporter GlyT1 is involved.

La présente invention concerne des composés qui inhibent le transporteur de glycine GlyT1 et qui sont utiles dans le traitement de maladies neurologiques et psychiatriques associées à un dysfonctionnement de la neurotransmission glycinergique ou glutamatergique et de maladies dans lesquelles le transporteur de glycine GlyT1 est impliqué.

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