4-phenylbutyric acid controlled-release formulations for...

Details 4-phenylbutyric acid controlled-release formulations for... 4-phenylbutyric acid controlled-release formulations for...

C - Chemistry, Metallurgy

08

K

C08K 5/00 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2582255

Controlled-release formulations and dosage forms containing 4-phenylbutyric acid sodium salt, or other pharmaceutically acceptable salts, esters or prodrugs, and a controlled release material for use in the treatment of diseases and disorders including neoplastic disorders and neurodegenerative diseases The formulations provide extended release and extended half-life.

L'invention concerne des formulations et des formes posologiques à libération contrôlée contenant du sel de sodium d'acide 4-phénylbutyrique, ou d'autres sels, esters ou pour médicaments acceptables sur le plan pharmaceutique, et une matière à libération contrôlée utilisée dans le traitement des maladies et de troubles notamment les troubles néoplastiques et les maladies neurodégénératives. Les formulations offrent libération prolongée et une demi-vie prolongée.

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