4-piperazinnylthieno [2,3-d] pyrimidine compounds as...

Details 4-piperazinnylthieno [2,3-d] pyrimidine compounds as... 4-piperazinnylthieno [2,3-d] pyrimidine compounds as...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2602358

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I), wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

L'invention concerne des composés et des sels de ceux-ci acceptables sur le plan pharmaceutique, ces composés possédant une structure de formule (I), dans laquelle A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5 et R6 sont tels que définis dans la description détaillée de l'invention. L'invention concerne également des compositions pharmaceutiques correspondantes, des procédés de traitement, des procédés de synthèse et des intermédiaires.

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