4-piperazinylthieno [2,3-d] pyrimidine compounds as platelet...

Details 4-piperazinylthieno [2,3-d] pyrimidine compounds as platelet... 4-piperazinylthieno [2,3-d] pyrimidine compounds as platelet...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2602227

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A1 , A2, A3, A4, A5, A6, A7, A8, X4, X6, R2k, R2I, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

L~invention concerne des composés et des sels pharmaceutiquement acceptables, les composés ayant une structure représentée par la formule (I) dans laquelle A1 , A2, A3, A4, A5, A6, A7, A8, X4, X6, R2k, R2I, R4, R5, et R6 sont tels que définis dans la description de l~invention. L'invention concerne également des compositions pharmaceutiques correspondantes, des procédés de traitement, des procédés de synthèse et des intermédiaires.

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