4-piperidinol tertiary amines as histamine 3 receptor...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/00 (2006.01) C07D 405/00 (2006.01)

Patent

CA 2594264

This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain non-imidazole tertiary amine derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.

L'invention concerne des composés possédant une activité pharmacologique, des compositions contenant ces composés et une méthode de traitement utilisant les composés et les compositions. Plus spécifiquement, cette invention a pour objet certains dérivés d'amine tertiaire sans imidazole et leurs sels et solvates. Ces composés possèdent une activité antagoniste du récepteur de l'histamine H3. Ladite invention a aussi trait à des compositions pharmaceutiques contenant ces composés et à une méthode de traitement de troubles, dans lesquels le blocage du récepteur de l'histamine H3 est bénéfique.

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