4-(polyalkoxy-phenyl)-2-pyrrolidone

Details 4-(polyalkoxy-phenyl)-2-pyrrolidone 4-(polyalkoxy-phenyl)-2-pyrrolidone

C - Chemistry, Metallurgy

07

D

260/323, 260/306

C07D 207/24 (2006.01) C07C 45/71 (2006.01) C07C 47/575 (2006.01) C07D 207/26 (2006.01) C07D 207/277 (2006.01)

Patent

CA 1069517

ABSTRACT OF THE DISCLOSURE A 4-(alkoxy-phenyl)-2-pyrrolidone of the general formula Image I wherein R1 and R2 each are hydrocarbon of up to 18 carbon atoms with at least one being other than methyl, a saturated hetero- cyclic ring with 5 ring members and a single O or S atom as the hetero atom, or alkyl of 1-5 carbon atoms substituted by one or more halogen atoms or by one of hydroxy, carboxy, alkoxy of 1-5 carbon atoms, alkoxycarbonyl of 1-5 carbon atoms in the alkoxy group, amino, alkylamino of dialkylamino wherein alkyl in each instance is of 1-5 carbon atoms, and X is an oxygen atom or a sulfur atom. The compounds generally exhibit central-depressive, apomorphine-antagonistic and anti-nociceptive action.

222720

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