4-pyrimidinyl-n-acyl-l-phenylalanines

Details 4-pyrimidinyl-n-acyl-l-phenylalanines 4-pyrimidinyl-n-acyl-l-phenylalanines

C - Chemistry, Metallurgy

07

D

C07D 239/06 (2006.01) A61K 31/505 (2006.01) A61P 1/04 (2006.01) A61P 19/02 (2006.01) C07D 239/46 (2006.01) C07D 239/54 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2392570

Coumpounds of Formula (1) are disclosed, wherein R1 to R6 are as defined in specification and which are inhibitors of binding between VCAM-1 and cells expressing VLA-4, and accordingly are useful for treating diseases whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4.

La présente invention concerne des composés de la formule (I), dans laquelle R?1¿ à R?6¿ sont tels que définis dans la description, qui sont des inhibiteurs de la liaison entre VCAM-1 et les cellules exprimant VLA-4, et qui sont par conséquent utilisés dans le traitement de maladies dont les symptômes et/ou les lésions sont liés à la liaison de VCAM-1 aux cellules exprimant VLA-4.

Affiliated with

Also associated with

Rating

4-pyrimidinyl-n-acyl-l-phenylalanines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-pyrimidinyl-n-acyl-l-phenylalanines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-pyrimidinyl-n-acyl-l-phenylalanines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1685860