4-quinoline carboxylic acid derivatives useful as...

Details 4-quinoline carboxylic acid derivatives useful as... 4-quinoline carboxylic acid derivatives useful as...

A - Human Necessities

61

K

167/226

A61K 31/47 (2006.01)

Patent

CA 1333155

4-Quinolinecarboxylic acids and derivatives thereof, such as 2-(2'-fluoro-1,1'-biphenyl-4-yl)- 6-fluoro-3-methyl-4-quinolinecarboxylic acid, are useful as immunomodulatory and anti-inflammatory agents. Pharmaceutical formulations containing such compounds are useful for the treatment of autoimmune diseases, transplantation rejection, graft vs. host disease, and chronic inflammatory disease such as rheumatoid arthritis.

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