4-quinolinyl derivatives with anti-helicobacter activity

Details 4-quinolinyl derivatives with anti-helicobacter activity 4-quinolinyl derivatives with anti-helicobacter activity

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/47 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2146651

The present invention is concerned with novel quinoline derivatives having anti-Helicobacter activity of formula (I), the pharmaceutically acceptable acid addition salts therof, the stereochemically isomeric forms thereof, the quaternized forms thereof and the N-oxides thereof, wherein -A- represents a bivalent radical of formula: (a) -N=CH-CH=CH-, (b) -CH=N-CH=CH-, (c) -N = N-CH = CH-, (d) -N = CH-N = CH-, (e) -N = CH-CH = N-, (f) -CH = N-N = CH-, (g) -N = N-N = CH-, (h) -N = N- CH = N-, or (i) -CH = CH-CH = CH-; R1, R2, R3, R4, R5, R6 and R7 each independently represent hydrogen, halo, hydroxy, C1-4alkyloxy, C1-4alkyl, trifluromethyl, amino, mono- or di(C1-4alkyl)- amio or nitro, provided that when one substituent on a phenyl group is a nitro then the other substituents on said phenyl group are other than nitro; novel compositions compris- ing said compunds, processes of preparing said compounds and compositions and methods for treating subjects suffering from disorders or afflictions associated with Helicobacter infection.

Affiliated with

Also associated with

Rating

4-quinolinyl derivatives with anti-helicobacter activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-quinolinyl derivatives with anti-helicobacter activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-quinolinyl derivatives with anti-helicobacter activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1973273