4-substituted 3-oxobutanoate ester derivatives

Details 4-substituted 3-oxobutanoate ester derivatives 4-substituted 3-oxobutanoate ester derivatives

C - Chemistry, Metallurgy

07

D

260/335.5

C07D 205/08 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1337354

This invention relates to a process for preparing 4-substituted 3-oxobutanoate ester derivatives by reaction of essentially anhydrous magnesium malonate monoester salts with activated acyl compounds; the process is useful for synthesizing intermediates for carbapenems; the essentially anhydrous magnesium malonate monoester salt is generated and used in situ.

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