4'-substituted-4,5',8-trialkylpsoralens

Details 4'-substituted-4,5',8-trialkylpsoralens 4'-substituted-4,5',8-trialkylpsoralens

C - Chemistry, Metallurgy

07

D

260/359.4

C07D 493/04 (2006.01)

Patent

CA 1141768

T.C.Elder 8 APPLICATION FOR LETTERS PATENT FOR 4'-SUBSTITUTED-4,5',8-TRIALKYLPSORALENS ABSTRACT OF THE DISCLOSURE The invention relates to 4,5',8-trialkylpsoralens, having a substituent on the 4' carbon atom which is selected from hydroxyalkoxyalkyl and hydroxyalkylaminoalkyl , which are characterized by enhanced photosensitizing activity, especially oral activity, including comparable maxima, early onset, and especially rapid decline, as well as low toxicity, when con- trasted with psoralens of different structure. Process for the production thereof. Inventor: KURT D. KAUFMAN 2205 Benjamin Avenue Kalamazoo, Michigan 49008

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