4-substituted androstendione derivatives and process for...

C - Chemistry – Metallurgy – 07 – J

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167/198, 260/37,

C07J 41/00 (2006.01) A61K 31/565 (2006.01) C07J 43/00 (2006.01)

Patent

CA 1319362

25521-113 ABSTRACT The invention discloses 4-substituted androstendione derivatives of the following formula (I) (I) Image wherein R is amino or azido, one of R1 and R2 is hydrogen and the other is hydrogen, alkyl, alkenyl or alkynyl, and (x) and (y) are each, independently, a single bond or a double bond. The compounds of formula (I) are useful aromatase inhibitors.

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