4-substituted isoquinolone derivatives, their production and...

Details 4-substituted isoquinolone derivatives, their production and... 4-substituted isoquinolone derivatives, their production and...

C - Chemistry, Metallurgy

07

D

167/226, 260/277

C07D 217/24 (2006.01) A61K 31/47 (2006.01) C07D 217/22 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2028538

ABSTRACT OF THE DISCLOSURE A compound of the formula (I): Image wherein X is -CH2-CH2- or -CH=CH-, Y is Image or Image , Z is an oxygen or sulfur atom, R1 and R2 are independently a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group and ring A is an optionally substituted 6-membered homocyclic ring, or its ester or salt which is useful as an inhibitory agent for the biosynthesis of the cholesterol.

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