4'-substituted nucleosides

Details 4'-substituted nucleosides 4'-substituted nucleosides

A - Human Necessities

61

K

A61K 31/7068 (2006.01) A61K 31/7076 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2449572

The present invention relates to the use of nucleoside derivatives of Formula (I) wherein B signifies a 9-purinyl residue B1 of Formula (B1) or a 1- pyrimidyl residue B2 of Formula (B2) wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.

La présente invention concerne l'utilisation de dérivés de nucléoside représentés par la formule (I) dans laquelle B désigne un résidu B1 de 9-purinyle de fornule (B1) ou un résidu B2 de 1-pyrimidyle de formule (B2) dans lesquelles les symboles ont la définition qui leur est attribuée dans le descriptif, ainsi que des sels pharmaceutiquement acceptables de ces dérivés pour le traitement de maladies induites par le virus de l'hépatite C (HCV), et pour la préparation d'un médicament pour un tel traitement et de compostions pharmaceutiques renfermant de tels composés.

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