4-substituted piperazine-2-carboxylic acids

C - Chemistry – Metallurgy – 07 – D

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C07D 241/04 (2006.01) C07D 403/06 (2006.01) C07F 9/6509 (2006.01)

Patent

CA 1248531

ABSTRACT "ORGANIC COMPOUNDS" Compounds of the general formula Image wherein X is C1-C6, straight chain saturated or unsaturated hydrocarbyl group, the group R4 and the group Y are situated in any position in this chain and wherein at least one of the hydrogen atoms in X can be a heavy isotope of hydrogen; R4 is hydrogen or an alkyl, alkoxy, hydroxy, aryl, aryloxy, aralkyl, aralkoxy, aralkylamino, or morpholino group wherein the alkyl or aryl part of any one of said groups may be substituted by one or more halogeno groups; or R , together with at least one carbon atom of the group X, forms a carbocyclic or heterocyclic ring of 5 to 6 ring atoms; Y is an acidic or related group giving rise to one or more electronegative sites in the group; or R4-X-Y represents a carboxylic acyl group; R is hydrogen or an alkyl, haloalkyl, aryl, haloaryl, aralkyl or haloaralkyl;

479065

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