4a-aryl-octahydro-1h-2-pyrindines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/06 (2006.01) C07D 211/70 (2006.01) C07D 221/04 (2006.01)

Patent

CA 1105026

-1- Abstract of the Disclosure Trans-4a-phenyl and substituted phenyl 2,3,4,?,5,6,7,7a-octahydro-1H-2-pyrindines having a 2-substituent are disclosed. Such compounds are useful as analgesic agents having mixed agonist and antagonist properties. The compounds can be prepared by reacting a 4a-aryl-2-substituted-3,4,4a, 5,6,7-hexahydro-2-pyrindine with hydrogen and platinum oxide.

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