4h-3,1-benzoxazin-4-one compounds and their pharmaceutical...

Details 4h-3,1-benzoxazin-4-one compounds and their pharmaceutical... 4h-3,1-benzoxazin-4-one compounds and their pharmaceutical...

C - Chemistry, Metallurgy

07

D

C07D 265/24 (2006.01) A61K 31/535 (2006.01) A61K 38/04 (2006.01) C07D 413/04 (2006.01) C07K 5/02 (2006.01) C07K 5/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2051115

- 73 - ABSTRACT 4H-3,1-Benzoxazin-4-one compounds represented by formu- la [I]: Image [I] and their salts, and pharmaceutical compositions containing the same as an active ingredient. They have inhibitory effect against protease, particularly inhibitory effect selective against human leukocyte elastase with high solu- bility in water and excellent tissue retention.

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