4h-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives

Details 4h-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives 4h-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives

C - Chemistry, Metallurgy

07

D

167/242, 260/328

C07D 333/80 (2006.01) A61K 31/38 (2006.01)

Patent

CA 1276158

ABSTRACT [2-Halo-10-oxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4- ylidene]acetic acids, for example of formula I (I) Image wherein R1 is H or C1-4alkyl and R2 is halogen, their physio- logically-hydrolysable and -acceptable esters, and salts thereof. Such compounds, esters and salts possess valuable pharmaceutical, in particular anti-inflammatory, antipyretic and analgesic, properties.

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