5-(1-aminocyclohexyl)-2(1h)-pyridinone and related compounds

Details 5-(1-aminocyclohexyl)-2(1h)-pyridinone and related compounds 5-(1-aminocyclohexyl)-2(1h)-pyridinone and related compounds

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) C07D 401/08 (2006.01) C07D 413/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2063594

There are described compounds of the formula (see formula 1) where n is 1, 2 or 3; R1 is hydrogen, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl, loweralkyl, arylloweralkyl, (see formula 2) or (see formula 3), R5 and R6 being independently loweralkyl or alternatively the group (see formula 4) taken as a whole is (see formula 5), (see formula 6), (see formula 7) or (see formula 8) -60- R2 is hydrogen, loweralkyl, loweralkenyl, arylloweralkyl, -CH2C.ident.CH, Image Image R7 and R9 being independently loweralkyl or alternatively the group Image taken as a whole is Image R3 is hydrogen or loweralkyl; and R4 is hydrogen or loweralkyl; which compounds are useful ae analgesic agents and also for treating various memory dysfunctions.

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