5,10-methylene-tetrahydrofolate as a modulator of a...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01)

Patent

CA 2082811

The present invention relates to the compound 5,10-methylene-tetrahydrofolate (CH2FH4), and its solution isomer FH4, therapeutic uses of these compounds, and compositions thereof. CH2FH4 and FH4 strongly modulate the in vivo antitumor effects of 5-Fluorouracil.

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