5,10-methylenetetrahydrofolic acid-cyclodextrin inclusion...

Details 5,10-methylenetetrahydrofolic acid-cyclodextrin inclusion... 5,10-methylenetetrahydrofolic acid-cyclodextrin inclusion...

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 31/505 (2006.01) A61K 31/715 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2100126

The invention relates to novel cyclodextrin inclusion compounds of 5,10-methylenetetrahydrofolic acid. The surprisingly good stability of these compounds makes possible their pharmaceutical use for the first time. The invention additionally relates to a process for the preparation of the said substances and their use for the preparation of medicaments.

La présente invention concerne de nouveaux composés d'inclusion de l'acide 5,10-méthylènetétrahydrofolique dans les cyclodextrines. La stabilité étonnante de ces composés rend possible leur utilisation en pharmacologie pour la première fois. L'invention concerne également un procédé pour la préparation desdites substances et leur utilisation pour la préparation de médicaments.

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