5,14-dihydrobenz[5,6]isoindolo[2,1-b] isoquinoline-8,13-dione

Details 5,14-dihydrobenz[5,6]isoindolo[2,1-b] isoquinoline-8,13-dione 5,14-dihydrobenz[5,6]isoindolo[2,1-b] isoquinoline-8,13-dione

C - Chemistry, Metallurgy

07

D

167/227, 260/271

C07D 471/04 (2006.01) A61K 31/47 (2006.01)

Patent

CA 1272198

ABSTRACT 5,14-Dihydrobenz[5,6]isoindolo[2,1-b]isoquinoline- 8,13-dione Image (I) exhibits anticancer activity. The compound can be prepared by reaction of 2-formyl-3-carboxyl- 1,2,3,4-tetrahydroisoquinoline with 1,4-naphthoquinone and is particularly suitably administered parenterally in microcrystalline suspension form.

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