5-{2-[(2-amino-2-oxoethyl)...

C - Chemistry – Metallurgy – 07 – D

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167/209, 260/238

C07D 281/10 (2006.01) A61K 31/55 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2027738

- 20 - ABSTRACT A compound, in the form of a pure diastereoisomer or a mixture thereof, of formula (I) (I) Image in which R1 represents a hydrogen atom or a C2-C4 alkanoyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, n represents an integer of from 0 to 3, and R3 represents either a phenyl group bearing from 1 to 3 substituents selected from halogen atoms and trifluoromethyl, methyl, C1-C4 alkoxy or alkylthio, nitro, cyano, carbamoyl, acetamido, methanesulphonamido, methoxycarbonyl or phenylcarbonyl groups, or an aromatic heterocyclic group; or a pharmacologically acceptable acid addition salt thereof.

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