5-(3,4-dihydrocarbostyril-6-yl)-3,6-dihydro-1,2,4-...

C - Chemistry – Metallurgy – 07 – D

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167/212, 260/243

C07D 417/10 (2006.01) A61K 31/54 (2006.01) C07D 417/04 (2006.01)

Patent

CA 1246065

Abstract A thiadiazine compound of the formula: Image a method for preparing said compound and a pharmaceutical composition containing said compound, wherein X is methylene which may be optionally substituted by an alkyl of up to 3 carbon atoms; R is hydrogen atom or methyl group; and n is an integer of 1 or 2. Since the compounds exhibit potent cardiotonic and coronary vasodilator activities and further inhibitory activity on platelet aggregation, they are useful as cardiotonic and antithrombotic drugs.

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