5-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo [c,f]...

Details 5-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo [c,f]... 5-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo [c,f]...

C - Chemistry, Metallurgy

07

D

260/238.6

C07D 281/02 (2006.01)

Patent

CA 1282781

- 15 - P R E C I S NOUVEAU DERIVE TRICYCLIQUE DENOMME ACIDE [(CHLORO-3 METHYL-6 DIOXO-5,5 DIHYDRO-6,11 DIBENZO (C,F,) THIAZEPINE (1,2)YL-11 ) AMINO] -5 PENTANOIQUE, ET SON PROCEDE DE PREPARATION. ADIR & COMPAGNIE 22 RUE GARNIER F-92200 NEUILLY SUR SEINE L'invention concerne l'acide [(chloro-3 méthyl-6 dioxo-5,5 dihydro-6,11 dibenzo (c,f) thiazépine (1,2) yl-11) amino ] -5 pentanoïque. caractérisé en ce que l'on condense un dérivé halogéné de formule III) Image - 16 - dans laquelle X représente un atome de chlore, ou de brome, avec un ester d'acide amino-5 pentanoïque, puis l'on saponifie l'ester tricyclique ainsi obtenu pour former l'acide [ (chloro-3 méthyl-6 dioxo-5,5 dihydro-6,11 dibenzo (c,f) thiazépine (1,2) yl-11) amino] -5 pentanoïque.

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