5-(4-pyridyl)-6-(4-fluorophenyl)-2,3-...

Details 5-(4-pyridyl)-6-(4-fluorophenyl)-2,3-... 5-(4-pyridyl)-6-(4-fluorophenyl)-2,3-...

C - Chemistry, Metallurgy

07

D

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C07D 513/04 (2006.01) A61K 31/425 (2006.01) C07D 213/50 (2006.01)

Patent

CA 1128947

"5-(4-PYRIDYL)-6-(4-FLUOROPHENYL)-2,3-DIHYDROIMIDAZO- [2,1-b]THIAZOLE" ABSTRACT OF THE DISCLOSURE 5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo- [2,1-b]thiazole has significant antiarthritic and immuno- regulatory activity compared with its 5,6-transposed isomer. The compound is prepared by reacting 4-(4-pyridyl)-5-(4-fluoro- phenyl)-2-mercaptoimidazole with a reactive ethylene dihalide then separating the isomeric mixture of products.

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