5-(4-vinyl or 4-ethynylbenzoyl)-1,2-dihydro-3h-...

Details 5-(4-vinyl or 4-ethynylbenzoyl)-1,2-dihydro-3h-... 5-(4-vinyl or 4-ethynylbenzoyl)-1,2-dihydro-3h-...

C - Chemistry, Metallurgy

07

D

167/233, 260/299

C07D 487/06 (2006.01) A61K 31/40 (2006.01) C07D 487/04 (2006.01)

Patent

CA 1229088

ABSTRACT OF THE DISCLOSURE Novel 5-(4-vinyl- or 4-ethynylbenzoyl)-1,2-dihydro-3H- pyrrolo[1,2-a]pyrrole-1-carboxylic acids represented by the formula Image and the pharmaceutically acceptable, non-toxic alkyl esters and salts thereof, wherein R is vinyl or ethynyl, and Y is hydrogen, a lower alkyl group having from 1 to 6 carbon atoms, chloro or bromo are disclosed as prophylactic and therapeutic anti-inflammatory agents, analgesic agents, platelet aggregation inhibitors, fibrinolytic agents and smooth muscle relaxants.

445355

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