5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 267/14 (2006.01) A61K 31/55 (2006.01) C07D 413/06 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2303295

The present invention relates to benzoxazepinones of formula (I), or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.

La présente invention porte sur des benzoxazépinones de la formule (I) ou sur des formes steréoisomères ou des mélanges de celles-ci, ou sur leurs formes de sels pharmaceutiquement acceptables, et qui sont utiles comme inhibiteurs de la transcriptase inverse du VIH. L'invention porte également sur des compositions pharmaceutiques et des kits de diagnostic les comprenant, ainsi que sur leurs procédés d'utilisation pour traiter les infections virales ou comme standard ou réactif de dosage.

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