5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine compounds

Details 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine compounds 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine compounds

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2726834

The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5- a]pyrazine derivatives of formula (I) wherein R1, R2, R3, and R4 are as described n the description, to salts, especially pharmaceutically acceptable salts thereof, and to the use of such com-pounds as medicaments; especially as orexin receptor antagonists.

La présente invention concerne des dérivés 5,6,7,8-tétrahydro-imidazo[1,5- a]pyrazine de formule (I). Dans la formule, R1, R2, R3 et R4 sont tels que décrits dans la description. Cette invention porte également sur les sels, notamment les sels pharmaceutiquement acceptables de ces composés et sur l'utilisation de ces composés en tant que médicaments; notamment en tant qu'antagonistes du récepteur d'orexine.

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