5,6-diaryl pyridines substituted in the 2- and 3-position,...

Details 5,6-diaryl pyridines substituted in the 2- and 3-position,... 5,6-diaryl pyridines substituted in the 2- and 3-position,...

C - Chemistry, Metallurgy

07

D

C07D 213/38 (2006.01) A61K 31/4418 (2006.01) A61P 1/00 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 213/40 (2006.01) C07D 213/42 (2006.01) C07D 213/64 (2006.01)

Patent

CA 2702012

The invention relates to compounds corresponding to formula (I): in which: - Q is an oxygen atom, a sulphur atom or an -NR1- radical; - Z is an -N(R3)XR4, -N(R3)COOR5 or -OCON(R3)R5 group with X being a -CO-, -SO2-, -CON(R6)- or -CSN(R6) group; - Y is an -R1', -OR5', -N(R3')X'R4', -N(R3')COOR5', -NR7'R8', -CON(R3')R5', - CSN(R3')R5', C(O)R2', -C(O)-O-R2', -SO2R2', -SO2N(R3')R5' or -OCON(R3')R5' group, with X' being a -CO-, -SO2-, -CON(R6')- or -CSN(R6')- group; -Ar1 and Ar2 are each, independently of one another, an unsubstituted or substituted phenyl, - k is 0 or 1; - m is 0 or 1; - and Alk' is a (C1-C7)alkyl group; in the form of a base or of an addition salt with an acid.

The invention relates to compounds corresponding to formula (I): in which: - Q is an oxygen alum, a sulphur atom or an -NR1- radical; - Z is an -N(R3)XR4, -N(R3)COOR5 or -OCON(R3)R5 group with X being a -CO-, -SO2-, -CON(R6)- or -CSN(R6) group; - Y is an -R1', -OR5', -N(R3)X l R4, -N(R3)COOR5, -NR7R8, - CON(R3)R5, - CSN(R3)R5, C(O)R2, -C(O)-O-R2, -SO2R2, -SO2N(R3)R5 or -OCON(R3)R5 group, with X' being a -CO-, -SO2-, - CON(R6)- or -CSN(R6)- group; -Ar and Ar2 are each, independently of one another, an unsubstituted or substituted phenyl, - k is 0 or 1; - m is 0 or 1; - and Alk' is a(C1-C7)alkyl group; in the form of a base or of an addition salt with an acid.

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