5,6-dihydro-4h-imidazo[2',1':2,3]imidazo-[4,5,1-ij]...

Details 5,6-dihydro-4h-imidazo[2',1':2,3]imidazo-[4,5,1-ij]... 5,6-dihydro-4h-imidazo[2',1':2,3]imidazo-[4,5,1-ij]...

C - Chemistry, Metallurgy

07

D

C07D 487/16 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) C07D 471/16 (2006.01)

Patent

CA 2148951

A compound of formula (I) Image (I) in which n represents the number 1 or 2, X represents a hydrogen atom or indicates that the phenyl ring to which it is attached is substituted by one or two substituents independently chosen from halogen, C1-C3 alkyl, C1-C3 alkoxy and hydroxyl, and R represents a hydrogen atom, a group of formula -CH2-CO2-R1 (in which R1 represents a hydrogen atom or a C1-C6 alkyl group) or a group of formula -CH2-CO-NR2R3 (in which each of R2 and R3 is independently a hydrogen atom or a C1-C3 alkyl group), or a pharmaceutically acceptable salt thereof, processes for their preparation and their use in the treatment of disorders of GABAergic transmission.

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