5,6-dihydronaphthalenyl derivatives having retinoid-like...

Details 5,6-dihydronaphthalenyl derivatives having retinoid-like... 5,6-dihydronaphthalenyl derivatives having retinoid-like...

C - Chemistry, Metallurgy

07

C

C07C 63/333 (2006.01) A61K 31/19 (2006.01) C07C 63/66 (2006.01) C07C 65/19 (2006.01) C07C 69/76 (2006.01)

Patent

CA 2344310

The 5,6-dihydronaphthalenyl derivatives of the formulae (I) and (II) possess potent retinoid-like activity against dermatological diseases with a substantially reduced irritancy profile when administered topically.

L'invention porte sur des dérivés de 5,6-dihydronaphtalényle des formules (I) et (II), qui ont une activité de type rétinoïde efficace contre les maladies dermatologiques tout en présentant une propriété irritante sensiblement réduite lorsqu'ils sont administrés sous forme de médicament topique.

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