5-(6-imidazo[1,2-a]pyridyl)pyridine derivative

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1309718

ABSTRACT OF THE DISCLOSURE 5-(6-Imidazo[1,2-a]pyridyl)pyridine derivatives represented by general formula; Image wherein x represents hydrogen atom or methyl group; Y represents cyano group, carboxamido group, hydrogen atom, amino group or a halogen atom; Z represents hydrogen atom or a lower alkyl group; W represents hydrogen atom or a lower alkyl group; R1 represents hydrogen atom, a lower alkyl group, phenyl group, a group shown by formula: -CH2R4 in which R4 is a lower alkoxy group, or a group shown by formula: Image in which R5 and R6 are hydrogen atom or a lower alkyl group; R2 represents hydrogen atom or a halogen atom; and R3 represents hydrogen atom, a lower alkyl group or a halogen atom; or a tautomer thereof; and pharmacologically acceptable salts thereof are disclosed . The 5- (6-imidazo [1, 2-a] pyridyl ) pyridine derivatives are effectivefor treating congestive heart failures.

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