5.alpha.-bicyclomycin derivatives

C - Chemistry – Metallurgy – 07 – D

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260/237.7

C07D 498/08 (2006.01) C07H 9/06 (2006.01)

Patent

CA 1093071

Case 4-10641/+ Canada Abstract of the Disclosure Bicyclomycin derivatives (i.e. compounds with the skeleton of the 5-methylene-2-oxa-7,9-diazabicyclo[4,2,2]decane) of the formula Image (I) wherein Ra to Rd represent hydrogen atoms or hydroxyl protective groups, X represents a free or functionally modified carboxyl group, a substituted or unsubstituted hydrocarbon radical or a halogen atom, and n is 0 or 1, possess valuable antibiotic properties which are of importance in particular for combating infections caused by Enterobacteriaceae and Proteus species.

283708

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