5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 491/056 (2006.01) A61K 31/4375 (2006.01) A61K 31/498 (2006.01) A61P 31/04 (2006.01) C07D 497/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2744456

The invention relates to antibacterial compounds of formula I wherein R1 represents alkoxy (notably methoxy); R2 represents H or F; each of R3, R4, R5 and R6 represents independently H or D; V represents CH and W represents CH or N or V represents N and W represents CH; Y represents CH or N; Z represents O, S or CH2; and A represents CH2, CH2CH2 or CD2CD2; and salts of such compounds.

L'invention porte sur des composés antibactériens de formule I, dans laquelle R1 représente un groupe alcoxy (notamment méthoxy); R2 représente H ou F; chacun de R3, R4, R5 et R6 représente indépendamment H ou D; V représente CH et W représente CH ou N, ou V représente N et W représente CH; Y représente CH ou N; Z représente O, S ou CH2; et A représente CH2, CH2CH2 ou CD2CD2; et sur des sels de tels composés.

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