5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as...

Details 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as... 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as...

C - Chemistry, Metallurgy

07

C

C07C 237/02 (2006.01) A61K 31/16 (2006.01) C07C 237/14 (2006.01) C07C 323/41 (2006.01)

Patent

CA 2191924

A series of 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives of Formula ? have been synthesized. See Fig. I (?) As inhibitors of the production of .beta.-amyloid protein from .beta.-amyloid precursor protein, these compounds are expected to be effective in treating patients suffering from or susceptible to conditions or disorders linked to brain accumulation of .beta.-amyloid protein; e.g., Alzheimer's Disease and Down's Syndrome.

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