5-aminoalkylpyrazolo[4,3-d]pyrimidines

Details 5-aminoalkylpyrazolo[4,3-d]pyrimidines 5-aminoalkylpyrazolo[4,3-d]pyrimidines

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) A61P 15/10 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2410399

The present invention relates to 5-aminomethylpyrazolo[4,3-d]pyrimidines of the general formula (I) (see formula I) in which the radicals R1 to R6 have the meaning indicated in the text. The compounds show phosphodiesterase V inhibition and can be employed for the treatment of conditions of the cardiovascular system and for the treatment of potency disorders.

L'invention concerne des 5-aminoalkyle-pyrazolo[4,3-d]pyrimidines de formule générale (I) dans laquelle les restes R<1> à R<6> ont la signification mentionnée dans le texte. Ces composés exercent une inhibition de la phosphodiestérase V et s'utilisent pour traiter des affections du système cardio-vasculaire, ainsi que des troubles de l'érection.

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