5-aminomethyl-2,3-dihydro-2-oxo-1h-imidazole-4- carboxylic...

C - Chemistry – Metallurgy – 07 – D

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260/305.1, 260/2

C07D 233/90 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1175827

ABSTRACT OF THE DISCLOSURE 2,3-Dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives having a (substltuted amino)methyl substituent at the 5-position, are useful as cardiotonics, antihyper- tensives and antithrombotic agents. The ccmpounds are obtained by the reaction of an appropriate amine with a 5-(bromomethyl)-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid ester or amide.

402078

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