C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/305.1, 260/2
C07D 233/90 (2006.01) C07D 403/06 (2006.01)
Patent
CA 1175827
ABSTRACT OF THE DISCLOSURE 2,3-Dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives having a (substltuted amino)methyl substituent at the 5-position, are useful as cardiotonics, antihyper- tensives and antithrombotic agents. The ccmpounds are obtained by the reaction of an appropriate amine with a 5-(bromomethyl)-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid ester or amide.
402078
Dage Richard C.
Grisar J. Martin
Schnettler Richard A.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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