C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) C07D 215/56 (2006.01)
Patent
CA 2102196
ABSTRACT A 5-aminoquinolone carboxylic acid derivative represented by the following general formula (1): Image (1) wherein R1 means a hydrogen atom, an amino group, a linear or branched alkyl group having 1-5 carbon atoms and an alkylamino group containing a linear or branched alkyl group having 1-5 carbon atoms, R2 denotes a hydrogen atom or a linear or branched alkyl group having 1-5 carbon atoms, X stands for a halogen atom, Y means CH2, NH, CHR3, NR3 (R3 denoting a linear or branched alkyl group having 1-5 carbon atoms) or an oxygen atom, and Z stands for an oxygen atom or 2 hydrogen atoms, or a salt thereof, and an antibacterial agent containing such a derivative or salt as an active ingredient. The derivative or salt thereof exhibits strong anti- bacterial activities against Grampositive bacteria including tolerant bacteria, and is satisfactorily absorbed in a living body.
Asaoka Takemitsu
Kaihoh Terumitsu
Konno Fujiko
Kuraishi Tadayuki
Matsuda Hideaki
Gowling Lafleur Henderson Llp
Ss Pharmaceutical Co. Ltd.
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