5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones and their use...

C - Chemistry – Metallurgy – 07 – D

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C07D 249/12 (2006.01) A61K 31/41 (2006.01) C07D 405/10 (2006.01)

Patent

CA 1284997

ABSTRACT This invention relates to novel compounds which are 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones, of the formula: Image wherein R is halogeno, C1-6 lower alkyl, C1-6 lower alkoxy, hydroxy, trifluoromethyl, or methylenedioxy; n is 1 or 2; and R2 and R4 independently represent C1-6 lower alkyl, said compounds being useful as antidepressants.

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