C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/96 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2632227
The invention provides N-cyclic sulfonamido compounds of Formula (I) wherein A, B, R1, R1a, R2, R2a, R3 and R3a are as described in the specification. Compounds of Formula (I) are useful in treating or preventing cognitive disorders, such as Alzheimer 's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I), methods of preparing compounds of formula (I), and methods of treating cognitive disorders, such as Alzheimer's disease.
La présente invention concerne des composés de sulfonamido N-cycliques de formule (I) dans laquelle A, B, R1, R1a, R2, R2a, R3 et R3a sont tels que décrits dans le mémoire descriptif. Les composés de formule (I) sont utiles pour le traitement ou la prévention de troubles de la cognition tels que la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques qui comprennent des composés de formule (I), des procédés de préparation de composés de formule (I) et de procédés de traitement de troubles de la cognition tels que la maladie d'Alzheimer.
Garofalo Albert W.
Jagodzinski Jacek J.
Konradi Andrei W.
Semko Christopher M.
Smith Jenifer L.
Elan Pharmaceuticals Inc.
Mbm Intellectual Property Law Llp
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