5 asa drug delivery system

Details 5 asa drug delivery system 5 asa drug delivery system

A - Human Necessities

61

K

167/166, 167/253

A61K 31/665 (2006.01) A61K 31/74 (2006.01) A61K 47/48 (2006.01) C07C 245/08 (2006.01)

Patent

CA 1200204

ABSTRACT The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.

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