5-(azolyloxyphenylcarbamoyl)barbituric acid derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/12 (2006.01) C07D 233/70 (2006.01) C07D 239/62 (2006.01) C07D 239/66 (2006.01) C07D 249/12 (2006.01) C07D 271/113 (2006.01) C07D 277/34 (2006.01) C07D 277/58 (2006.01) C07D 277/68 (2006.01) C07D 285/08 (2006.01) C07D 285/13 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1280114

5-(Azolyloxyphenylcarbamoyl)barbituric acid derivatives as anthel- mintics Abstract of the Disclosure The invention relates to novel 5-(azolyloxyphenylcarbsmoyl)barbi- turic acid derivatives of the general formula I Image (I) wherein X in oxygen or sulfur; R1 is C1-C6alkyl, C1-C6alkoxy, C3-C6cycloalkyl or allyl; R2 is C1-C6alkyl or allyl; R3 is an unsubstituted or substituted five-membered azole ring which is bound through carbon and is selected from the group consisting of benzimidazole, benzoxazole, benzothiazole, imidazole, oxazole, thiazole, oxadiazole, thiadiazole and triazole; and R4 and R5 are each independently of the other hydrogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy or C1-C6haloalkoxy; and to the tautomers and salts thereof, as anthelmintic compounds. Together with suitable carriers and further assistants, these compounds may be used in particular for controlling helminths which are parasites of animals.

501752

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