5-(benz- (z) -ylidene) -thiazolidin-4-one derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/20 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 37/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2545582

The invention relates to pharmaceutical compositions containing at least one 5- (benz- (Z) -ylidene-thiazolidin-4-one derivative (I), to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.

L'invention concerne des compositions pharmaceutiques contenant au moins un dérivé de thiazoline-4-one (I), utilisées pour prévenir ou traiter des troubles associés à un système immunitaire activé. L'invention concerne en outre de nouveaux dérivés de thiazoline-4-one, s'utilisant notamment comme composés pharmaceutiquement actifs. Lesdits composés agissent en particulier comme agents immunodépresseurs. Formule générale (I)

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