C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/61 (2006.01) A61K 31/444 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2410234
This invention encompasses the Form V polymorph of Compound A of structural formula (A) which is useful in the treatment of cyclooxygenase-2 mediated diseases. The invention encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising the Form V polymorph of Compound A. The invention also encompasses a process for synthesizing the Form V polymorph of Compound A.
Cette invention concerne le polymorphe de forme V du composé A, représenté par la formule (A), qui convient bien pour le traitement de maladies induites par la cyclooxygénase-2. L'invention concerne certaines préparations pharmaceutiques utilisées pour le traitement de maladies induites par la cyclooxygénase-2, qui renferment le polymorphe de forme V du composé A. Cette invention concerne également un procédé de synthèse du polymorphe de forme V du composé A.
Crocker Louis S.
Davies Ian W.
Kotliar Andrew
Osifchin Richard G.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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